REGULATION OF EDHFR-TAGGED PROTEINS WITH TRIMETHOPRIM PROTACS

Regulation of eDHFR-tagged proteins with trimethoprim PROTACs

Abstract Temporal control of protein levels in cells and living animals can be used to improve our understanding of protein function.In addition, control of engineered proteins could be used in therapeutic applications.PRoteolysis-TArgeting Chimeras (PROTACs) have emerged as a small-molecule-driven strategy to achieve rapid, post-translational regu

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Privacy-Aware Collaborative Learning for Skin Cancer Prediction

Cancer, including the highly dangerous melanoma, is marked by uncontrolled cell growth and the possibility of spreading to other parts of the body.However, the conventional approach to machine learning relies on centralized training data, posing challenges for Table Runner data privacy in healthcare systems driven by artificial intelligence.The col

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Social Struggle and Faith-Based Activism in Black Empowerment times: An agenda for postcolonial mission - sounding the horn on some African perspectives

This paper identifies and outlines certain key issues in the discourse on postcolonial mission, recognizing that half-a-century after decolonization and independence, and after the shift in World Christianitys centre of gravity from Western Europe to the Global South, the legacies of colonialism are still very Hair Clips much with us.From a Two-Thi

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